ALK-positive primary systemic anaplastic large cell lymphoma with extensive cutaneous manifestation.

نویسندگان

  • Kazuha Ando
  • Yasuhiko Tamada
  • Kazuyuki Shimizu
  • Yoichi Akita
  • Daisuke Watanabe
  • Shigeru Nakamura
  • Kazuo Hara
  • Yoshinari Matsumoto
چکیده

localization of keratins and involucdn in solar keratosis and Bowen's disease. Am J Dermatopathol 1995; 17: 151-157. 4. Mai K.T. Alhalouly T. Landry D, Stinson WA. Perkins DG, Yazdi HM. Pagetoid variant of actinic keratosis with or with -out squamous cell carcinoma of sun-exposed skin: a lesion simulating extramammary Paget's disease. Histopathology 2002; 41:331-336. 5. Ansai S. Mihara I. Sebaceous carcinoma arising on actinic keratosis. Fur J Dermatol 2000; 10: 385-388. 6. Saida T, Okabe Y, Uhara H. Bowen's disease with itivasive carcinoma showing sweat gland differentiation. J Cutan Pathol 1989; 16:222-226. 7. Abenoza P, Ackerman AB. Neoplasm with eccrine differentiation. In: Abenoza P, Ackerman AB, editors. Ackennan's histologie diagnosis of neoplastic skin disease. Philadelphia: Lea and Febiger; 1990: p. 113-185. 8. Misago N, Narisawa Y. Sebaceous carcinoma with apocrine differentiation. Am J Dermatopathol 2001; 23: 50-57. 9. Ng WK. Nevus sebaceous with apocrine and sebaceous differentiation. Am J Dermatopathol 1996; 18 :420^23.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Anaplastic Large Cell Lymphoma Associated with Breast Implant: A Case Report

Primary breast lymphoma represents less than 1% of all primary breast malignancies and most primary breast lymphomas are of B-Cell origin. The association of anaplastic lymphoma kinase (ALK) negative anaplastic large cell lymphoma (ALCL), a very rare form of primary breast lymphoma, with silicone-filled breast implants has been suggested and several case reports supported this proposal, especia...

متن کامل

ALK-positive anaplastic large cell lymphoma limited to the skin: clinical, histopathological and molecular analysis of 6 pediatric cases. A report from the ALCL99 study.

Anaplastic large cell lymphomas are peripheral T-cell lymphomas that are characterized by a proliferation of large anaplastic blasts expressing CD30. In children, systemic anaplastic large cell lymphomas often present at advanced clinical stage and harbor translocations involving the anaplastic lymphoma kinase (ALK) gene leading to the expression of chimeric anaplastic lymphoma kinase (ALK)-fus...

متن کامل

CD30-Positive Anaplastic Lymphoma Kinase-Negative Systemic Anaplastic Large-Cell Lymphoma in a 9-Year-Old Boy

Anaplastic large-cell lymphoma (ALCL) is a CD30-positive T-cell/null-cell lymphoma that is clinically classified into either primary cutaneous ALCL or systemic ALCL (S-ALCL) sub-types. Because 90% of childhood S-ALCL cases are anaplastic lymphoma kinase (ALK)-positive, there is a lack of data on ALK-negative S-ALCL cases among pediatric patients. Herein, we report a rare case of ALK-negative S-...

متن کامل

Brain metastasis of ALK positive anaplastic large cell lymphoma after a long-term disease free survival in an old adult.

Anaplastic large cell lymphoma (ALCL) is a subtype of non-Hodgkin lymphoma composed of CD30-positive cells and now recognized as three different entities: primary cutaneous ALCL, primary systemic anaplastic lymphoma kinase (ALK)-positive (ALK+) ALCL and primary ALK-negative (ALK-) ALCL. ALK+ ALCL is supposed to have a better prognosis than ALK- ALCL. It is rarely metastasized to other sites, es...

متن کامل

Systemic and primary cutaneous anaplastic large cell lymphoma: Clinical features, morphological spectrum, and immunohistochemical profile

BACKGROUND T-cell lymphomas with anaplastic morphology typically comprise of anaplastic lymphoma kinase positive, anaplastic large cell lymphoma (ALK+ ALCL), ALK-negative ALCL (ALK- ALCL), and primary cutaneous ALCL (PC-ALCL). However, other entities such as diffuse large B-cell lymphoma, peripheral T-cell lymphoma, Hodgkin lymphoma, and undifferentiated carcinoma can also show similar anaplast...

متن کامل

Anaplastic Lymphoma Kinase in Cutaneous Malignancies

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that has been implicated in the pathogenesis of a variety of neoplasms. As suggested by its name, ALK was first described as part of a translocation product in cases of anaplastic large-cell lymphoma, with other genetic and cytogenetic ALK mutations subsequently coming to attention in the development of many other hematologic and so...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Acta dermato-venereologica

دوره 90 2  شماره 

صفحات  -

تاریخ انتشار 2010